Background. Xiaotong Tiegao (XTT) is an ancient topical Tibetan medicine plaster which is widely used in China. Irritant contact\ndermatitis (ICD) caused by XTT is very common. It is still unclear why some people aremore prone to develop ICD.Theaimof this\nstudy is to study the baseline skin biophysical parameters and patch test results in individuals predisposing to XTT induced ICD.\nMethods. During a four-month period, 149 healthy volunteers with ICD and 50 volunteers without ICD after applying XTT were\nrecruited. The skin biophysical parameters were measured, and contact allergy to 20 common allergens was patch tested, at two\nweeks after the ICD was recovered. Results.There were no significant differences in age and sex between ICD and control groups. It\nwas found that skin median melanin value (176.50 vs 189.50, P < 0.05, Mann-Whitney U-test) and erythema value....................
Loading....